Researchers have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is first formed after fertilization, each cell has the ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

Researchers from the Kind Group have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is first formed after fertilization ...

An illustration of multicolored tangle of threads within a small black sphere. A 3D illustration shows DNA packaged into the nucleus, scientists with the 4D Nucleome project are now building accurate ...

An article by UAB professor Joan-Ramon Daban analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study ...

DNA has to be carefully packaged and organized in cells so it will both physically fit into the nucleus, and also remain accessible to the cellular machinery that transcribes active genes. Together, ...

Left: staining for H3K27me3, which marks inactive DNA, on a nucleus of a wildtype embryo consisting of two cells Right: staining for H3K27me3, which marks inactive DNA, on a nucleus of an embryo ...