Scientists are exploring ways to mimic the origins of human life without two fundamental components: sperm and egg. They are coaxing clusters of stem cells – programmable cells that can transform into ...

Researchers have used stem cells to develop new human embryolike structures that model the earliest stages of fetal development so realistically that they even secrete hormones that can turn a lab ...

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Formation of the energy-producing machinery in the proximal tubule of the nephron is an essential step in differentiation. The authors show that mitochondrial localization depends on LRRK2, the ...

The most advanced lab-made human embryo models look like the real thing — they resemble, though don't perfectly replicate, natural embryos about 14 days into development. These lab-made embryo models ...

Under his microscope, Jun Wu could see several tiny spheres, each less than 1 millimetre wide. They looked just like human embryos: a dark cluster of cells surrounded by a cavity, and then another ...

For decades, animal models have been the gold standard for preclinical testing of potential drugs. Yet, even the best animal models are not perfect. For example, small rodent species with engrafted ...