MSP: Methylation-specific PCR; MSRE: Methylation-sensitive restriction endonucleases; QMSP: Quantitative, methylation-specific PCR; X: Methylation associated with prognosis. Mohammad Obaidul Hoque, ...

A unique community-based family cancer registry. Background: Currently, no definite epigenetic markers exist to predict tumor recurrence after surgical resection in patients (pts) with BC. We studied ...

The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.

Clinical outcome of triple-negative primary breast cancer in older women: Comparison with their younger counterparts. Background: BRCA1 plays a central role repairing DNA double-strand breaks via ...