Supercritical fluid chromatography, or SFC, has been around for decades. During that time, the separation technique has fallen in and out of and back in favor. But it has consistently been relegated ...

Supercritical Fluid Chromatography (SFC) techniques represent an evolving analytical separation method that harnesses the unique properties of supercritical fluids—predominantly carbon dioxide—to ...

The authors demonstrate that using supercritical fluid chromatography offers distinct advantages in speed and in clean isolation of the desired peaks. Isolation of trace impurities and degradants from ...

High-performance liquid chromatography (HPLC) for enantiomeric separation of chiral active pharmaceutical ingredients took the drug industry by storm in the late 1990s. Drug companies needed a ...

High-performance liquid chromatography and gas chromatography are tried and true analytical chemistry techniques. However, an underappreciated forerunner, supercritical fluid chromatography (SFC), is ...

The combination of supercritical fluid chromatography with chiral separation media offers several analytival advantages over traditional liquid chromatography techniques. By itself, supercritical ...

Scientists engaged in drug development research depend on analytical chemistry techniques that allow them to separate compounds in preparation for downstream workflows. However, traditional separation ...

Join Madison Roeckel and Michael Stewart, our duo BUCHI experts, as they explain how prep SFC is as an eco-friendly and cost-effective solution for chromatographic separations. Watch the video and ...

Supercritical fluid chromatography (SFC) is a separation method that uses supercritical carbon dioxide as the mobile phase. Due to recent advancements in SFC instruments and column technologies, SFC ...