No reaction is more elegant, more heartwarmingly satisfying than the Diels-Alder reaction. No reaction is also more nuanced. It appears deceptively simple and yet has the ability to create immense ...

Figure 1: Details of individual reaction steps with macrophomate synthase. Figure 3: Active site view showing Mg 2+ coordination, the electron density map, and the proposed model of the early ...

Diels-Alder reloaded: More effective with electricity The chemist cites the Diels-Alder reaction as a current example. For three quarters of a century, it has had a firm place in organic chemistry, ...

Using computational design and directed evolution, scientists have successfully created a metalloprotein that can catalyze a commonly used organic reaction more efficiently than any known enzyme (Nat.