Figure 1: FPP synthesis and mevalonate pathway. In the present work, we determine a crystal structure of FPPS in complex with FPP. Intriguingly, the product is bound not to the active site, but to the ...

Sodium acid pyrophosphate is a food additive that is recognized as safe by the U.S. Food and Drug Administration. While generally harmless in small amounts, excessive phosphate intake can pose health ...

Please provide your email address to receive an email when new articles are posted on . Utilization of pyrophosphate imaging to identify patients with cardiac amyloidosis has increased, although ...

This article was originally published in HCPLive® and has been lightly edited. The risk of fractures is almost doubled for individuals with acute calcium pyrophosphate crystal arthritis compared to ...

In a first-of-its-kind genome-wide association study (GWAS) researchers have discovered two genes, RNF144B and ENPP1, that cause calcium pyrophosphate deposition (CPPD) disease in Americans of ...

Many of the modern DNA sequencing techniques involve partially overlapping methods, so our past articles have provided a nice foundation. In this case, the tethered PCR approach that we mentioned in ...