In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...

It has been claimed that because most of our DNA is active, it must be important, but now human-plant hybrid cells have been ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

A new study shows human immune systems differ across populations, raising new questions for medicine and global drug research ...

A giant functional atlas of immune cells in a Chinese cohort reveals crucial differences with European and Japanese data sets ...

A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...

Researchers in Japan built a miniature human brain circuit using fused stem-cell–derived organoids, allowing them to watch ...

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature. Chromosomes are thread-like structures that carry a cell's ...

Folic acid, also known as vitamin B9, is an important B-vitamin with many vital functions in the human body. It was discovered in the early 1930s when an English scientist isolated a compound from ...

An HIV-derived nucleoside therapy now treats rare genetic diseases by restoring mitochondrial DNA and improving muscle ...

The research represents a major step forward in revealing how the three dimensional form of DNA shapes the way human biology functions. In a major step toward understanding how the physical form of ...