B vitamins have many different benefits for your body. These nutrients can help turn calories into energy. Plus, they play an important role in keeping your eyes, nervous system, and skin, hair, and ...

Ikoma, Japan—Gram-negative bacteria pose a significant threat to global health due to their high resistance to antibiotics compared to that of Gram-positive bacteria. Their formidable defensive ...

I performed a 20 ns MD simulation and ran the following mmpbsa.in for gmx_MMPBSA: Be careful with the variables you modify, some can have severe consequences on the results you obtain. # General ...

I found that there is no binding between the ligand and the protein, which means the ligand molecule is just flying away or around the protein. The complexes that I think have this problem are 2BMV, ...

In this convincing work by Yamaguchi et al. the cryo-EM structure of the heterohexameric 3:3 LGI1-ADAM22 complex is presented. The findings suggest that LGI1 can cluster ADAM22 in a trimeric fashion.

Recently, SandboxAQ launched what it claims is the largest publicly available dataset of protein-ligand pairs with annotated experimental binding potency data. According to the company, the ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Free-energy perturbation (FEP) calculations have emerged as a promising tool for the ...

Ligand Pharmaceuticals’ topical skin infection gel Zelsuvmi is changing hands again—sort of. After Ligand last year created Pelthos Therapeutics to support the launch of Zelsuvmi, Pelthos is now ...